2. Gene
  3. Tnnt1 - troponin T1, skeletal, slow Gene

Tnnt1 - troponin T1, skeletal, slow Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tnt; sTnT; ssTnT

Gene ID: 21955 | Gene type: protein coding

About Tnnt1

Summary

This gene encodes the slow skeletal tropomyosin-binding subunit of the troponin complex and plays an essential role in the regulation of striated muscle contraction. In humans, mutations in this gene are associated with nemaline myopathy type 5. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]

Tnnt1 Products(4)

mRNA Protein Name
NM_001277903.1 NP_001264832.1 troponin T, slow skeletal muscle isoform 1
NM_001277904.1 NP_001264833.1 troponin T, slow skeletal muscle isoform 3
NM_001360154.1 NP_001347083.1 troponin T, slow skeletal muscle isoform 4
NM_011618.2 NP_035748.1 troponin T, slow skeletal muscle isoform 2
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within transition between fast and slow fiber IDA
IDA: Inferred from direct assay
18978355 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

troponin T, slow skeletal muscle

skeletal muscle slow-twitch TnT

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14854 TNNT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20117 Tnnt1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26621 Tnnt1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnnt1 NCBI NCBI:7138