2. Gene
  3. Tnfsf8 - tumor necrosis factor (ligand) superfamily, member 8 Gene

Tnfsf8 - tumor necrosis factor (ligand) superfamily, member 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CD153; Cd30l; CD30LG; Tnlg3a

Gene ID: 21949 | Gene type: protein coding

About Tnfsf8

Summary

Predicted to enable cytokine activity and tumor necrosis factor receptor binding activity. Acts upstream of or within CD8-positive, alpha-beta T cell differentiation; defense response to Gram-positive bacterium; and positive regulation of transcription by RNA polymerase II. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Orthologous to human TNFSF8 (TNF Superfamily member 8). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf8 Products(1)

mRNA Protein Name
NM_009403.3 NP_033429.1 tumor necrosis factor ligand superfamily member 8
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within CD8-positive, alpha-beta T cell differentiation IMP
IMP: Inferred from mutant phenotype
16177108 MGI
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
16177108 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
16177108 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
16177108 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 8

CD30 ligand

CD30-L

tumor necrosis factor ligand 3a

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14829 TNFSF8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174512 Human TNFSF8 mRNA / Unkown
HY-RS18100 Tnfsf8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24574 Tnfsf8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfsf8 NCBI NCBI:944
Macaca fascicularis Tnfsf8 NCBI NCBI:102143966
Rattus norvegicus Tnfsf8 NCBI NCBI:683163