2. Gene
  3. Tiam1 - T cell lymphoma invasion and metastasis 1 Gene

Tiam1 - T cell lymphoma invasion and metastasis 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as D16Ium10; D16Ium10e

Gene ID: 21844 | Gene type: protein coding

About Tiam1

Summary

Enables several functions, including guanyl-nucleotide exchange factor activity; microtubule binding activity; and signaling receptor binding activity. Involved in several processes, including activation of GTPase activity; brain-derived neurotrophic factor receptor signaling pathway; and regulation of dopaminergic neuron differentiation. Acts upstream of or within Ephrin Receptor signaling pathway; positive regulation of axonogenesis; and small GTPase mediated signal transduction. Located in kinocilium; pericentriolar material; and plasma membrane. Is expressed in several structures, including alimentary system; embryo ectoderm; gonad; sensory organ; and skin. Orthologous to human TIAM1 (TIAM Rac1 associated GEF 1). [provided by Alliance of Genome Resources, Apr 2022]

Tiam1 Products(3)

mRNA Protein Name
NM_001145886.1 NP_001139358.1 rho guanine nucleotide exchange factor TIAM1 isoform 1
NM_001145887.1 NP_001139359.1 rho guanine nucleotide exchange factor TIAM1 isoform 2
NM_009384.3 NP_033410.2 rho guanine nucleotide exchange factor TIAM1 isoform 1
Protein Preferred Names Protein Names

rho guanine nucleotide exchange factor TIAM1

T-lymphoma invasion and metastasis-inducing protein 1

TIAM-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16659 EHT 1864 Inhibitor 99.85% Unkown
HY-104064 1A-116 99.72% Unkown
HY-115376 Z62954982 Inhibitor 99.38% Unkown
HY-P1382A Rac1 Inhibitor W56 TFA Inhibitor 99.92% Unkown
HY-P1382 Rac1 Inhibitor W56 Inhibitor / Unkown
HY-RS14515 TIAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18300 Tiam1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24778 Tiam1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tiam1 NCBI NCBI:7074