2. Gene
  3. Tcn2 - transcobalamin 2 Gene

Tcn2 - transcobalamin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tcn-2

Gene ID: 21452 | Gene type: protein coding

About Tcn2

Summary

Predicted to enable cobalamin binding activity. Predicted to be involved in cobalamin transport. Predicted to act upstream of or within cobalt ion transport. Located in extracellular space. Is expressed in eye and genitourinary system. Human ortholog(s) of this gene implicated in Parkinson's disease; megaloblastic anemia; and transcobalamin II deficiency. Orthologous to human TCN2 (transcobalamin 2). [provided by Alliance of Genome Resources, Apr 2022]

Tcn2 Products(3)

mRNA Protein Name
NM_001130458.1 NP_001123930.1 transcobalamin-2 precursor
NM_001130459.1 NP_001123931.1 transcobalamin-2 precursor
NM_015749.3 NP_056564.1 transcobalamin-2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables cargo receptor ligand activity IDA
IDA: Inferred from direct assay
237480 MGI
enables cobalamin binding IDA
IDA: Inferred from direct assay
21655200 MGI
enables molecular carrier activity IDA
IDA: Inferred from direct assay
21655200 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cobalamin transport IDA
IDA: Inferred from direct assay
237480 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in external side of plasma membrane IDA
IDA: Inferred from direct assay
237480 MGI
is active in extracellular space IDA
IDA: Inferred from direct assay
21655200 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcobalamin-2

TC II

TC-2

TCII

transcobalamin II

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14319 TCN2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19166 Tcn2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25655 Tcn2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tcn2 NCBI NCBI:6948