2. Gene
  3. Ubtf - upstream binding transcription factor, RNA polymerase I Gene

Ubtf - upstream binding transcription factor, RNA polymerase I Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as UBF; UBF1; UBF-1; NOR-90; Tcfubf; A930005G04Rik

Gene ID: 21429 | Gene type: protein coding

About Ubtf

Summary

Predicted to enable several functions, including RNA polymerase I general transcription initiation factor activity; RNA polymerase I transcription regulatory region sequence-specific DNA binding activity; and scaffold protein binding activity. Involved in positive regulation of transcription by RNA polymerase I. Acts upstream of or within cellular response to leukemia inhibitory factor; rDNA heterochromatin assembly; and transcription elongation from RNA polymerase I promoter. Located in nucleolus. Is expressed in several structures, including brain; branchial arch; early conceptus; genitourinary system; and limb. Orthologous to human UBTF (upstream binding transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Ubtf Products(22)

mRNA Protein Name
NM_001044383.4 NP_001037848.1 nucleolar transcription factor 1 isoform 2
NM_001302954.3 NP_001289883.1 nucleolar transcription factor 1 isoform 2
NM_001302955.3 NP_001289884.1 nucleolar transcription factor 1 isoform 3
NM_001362544.2 NP_001349473.1 nucleolar transcription factor 1 isoform 1
NM_001362545.2 NP_001349474.1 nucleolar transcription factor 1 isoform 1
NM_001362547.2 NP_001349476.1 nucleolar transcription factor 1 isoform 2
NM_001362548.2 NP_001349477.1 nucleolar transcription factor 1 isoform 2
NM_001362549.2 NP_001349478.1 nucleolar transcription factor 1 isoform 4
NM_001362552.2 NP_001349481.1 nucleolar transcription factor 1 isoform 7
NM_001404620.1 NP_001391549.1 nucleolar transcription factor 1 isoform 2
NM_001404621.1 NP_001391550.1 nucleolar transcription factor 1 isoform 2
NM_001404622.1 NP_001391551.1 nucleolar transcription factor 1 isoform 2
NM_001404623.1 NP_001391552.1 nucleolar transcription factor 1 isoform 1
NM_001404624.1 NP_001391553.1 nucleolar transcription factor 1 isoform 2
NM_001404625.1 NP_001391554.1 nucleolar transcription factor 1 isoform 2
NM_001404626.1 NP_001391555.1 nucleolar transcription factor 1 isoform 2
NM_001404627.1 NP_001391556.1 nucleolar transcription factor 1 isoform 1
NM_001404628.1 NP_001391557.1 nucleolar transcription factor 1 isoform 1
NM_001404629.1 NP_001391558.1 nucleolar transcription factor 1 isoform 3
NM_001404630.1 NP_001391559.1 nucleolar transcription factor 1 isoform 3
NM_001404633.1 NP_001391562.1 nucleolar transcription factor 1 isoform 8
NM_011551.8 NP_035681.2 nucleolar transcription factor 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11592397 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
involved in positive regulation of transcription by RNA polymerase I IDA
IDA: Inferred from direct assay
20168301 MGI
acts upstream of or within transcription elongation by RNA polymerase I IDA
IDA: Inferred from direct assay
23562818 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleolus IDA
IDA: Inferred from direct assay
11555636 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleolar transcription factor 1

transcription factor UBF

upstream-binding factor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15393 UBTF Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19167 Ubtf Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25656 Ubtf Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ubtf NCBI NCBI:7343