2. Gene
  3. Tac1 - tachykinin 1 Gene

Tac1 - tachykinin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SP; NK1; NK-1; Nkna; PPTA; PPT-A; 4930528L02Rik

Gene ID: 21333 | Gene type: protein coding

About Tac1

Summary

Predicted to enable Neurokinin Receptor binding activity and receptor ligand activity. Acts upstream of or within several processes, including cellular response to nerve growth factor stimulus; response to pain; and sensory perception of pain. Located in axon; extracellular region; and neuronal cell body. Is expressed in several structures, including alimentary system; integumental system; limb; nervous system; and sensory organ. Orthologous to human TAC1 (tachykinin precursor 1). [provided by Alliance of Genome Resources, Apr 2022]

Tac1 Products(2)

mRNA Protein Name
NM_001311060.2 NP_001297989.1 protachykinin-1 isoform 2 precursor
NM_009311.3 NP_033337.1 protachykinin-1 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
31146259 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to nerve growth factor stimulus IDA
IDA: Inferred from direct assay
24760869 MGI
acts upstream of or within inflammatory response IDA
IDA: Inferred from direct assay
15159534 MGI
acts upstream of or within response to pain IMP
IMP: Inferred from mutant phenotype
11805341 MGI
acts upstream of or within sensory perception of pain IMP
IMP: Inferred from mutant phenotype
9537322 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
1317267 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
9537322 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
9853118 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protachykinin-1

neurokinin 1

neurokinin A

preprotachykinin A

substance P

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14136 TAC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18639 Tac1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25124 Tac1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tac1 NCBI NCBI:6863