2. Gene
  3. Sucla2 - succinate-Coenzyme A ligase, ADP-forming, beta subunit Gene

Sucla2 - succinate-Coenzyme A ligase, ADP-forming, beta subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A-SCS; SCS-betaA; 4930547K18Rik

Gene ID: 20916 | Gene type: protein coding

About Sucla2

Summary

Predicted to enable succinate-CoA Ligase (ADP-forming) activity and succinate-CoA Ligase (GDP-forming) activity. Predicted to be involved in succinate metabolic process; succinyl-CoA metabolic process; and tricarboxylic acid cycle. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study mitochondrial DNA depletion syndrome 5. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 5. Orthologous to human SUCLA2 (succinate-CoA Ligase ADP-forming subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Sucla2 Products(2)

mRNA Protein Name
NM_001361638.1 NP_001348567.1 succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial isoform 2
NM_011506.4 NP_035636.1 succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial isoform 1 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
part of succinate-CoA ligase complex (ADP-forming) IMP
IMP: Inferred from mutant phenotype
24271779 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

ATP-specific succinyl-CoA synthetase subunit beta

succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial

succinyl-CoA synthetase beta-A chain

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14000 SUCLA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21951 Sucla2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28468 Sucla2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sucla2 NCBI NCBI:8803