Ssb - small RNA binding exonuclease protection factor La Gene

Mus musculus

Also known as SS-B

Gene ID: 20823 | Gene type: protein coding

About Ssb

Summary

Enables RNA binding activity. Predicted to be involved in several processes, including IRES-dependent viral translational initiation; RNA metabolic process; and protein localization to cytoplasmic stress granule. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; gonad; sensory organ; and spleen. Orthologous to human SSB (small RNA binding exonuclease protection factor La). [provided by Alliance of Genome Resources, Apr 2022]

Ssb Products(3)

mRNA	Protein	Name
NM_001110145.1	NP_001103615.1	lupus La protein homolog isoform a
NM_001355265.1	NP_001342194.1	lupus La protein homolog isoform b
NM_009278.4	NP_033304.1	lupus La protein homolog isoform a

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA binding	IDA IDA: Inferred from direct assay	17971306	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	11817591	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

lupus La protein homolog

La protein	Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog)
Sjogren syndrome antigen B	autoantigen La
la autoantigen homolog	la ribonucleoprotein

Related Agents

Approval

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10617A	Rucaparib	Inhibitor	99.97%	Unkown
HY-10617	Rucaparib phosphate	Inhibitor	99.76%	Yes
HY-102003	Rucaparib monocamsylate	Inhibitor	99.91%	Yes
HY-102003A	Rucaparib camsylate	Inhibitor	/	Unkown

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-145804	Palacaparib	Inhibitor	98.30%	Phase 2

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-137457	Venadaparib	Inhibitor	98.11%	Unkown
HY-122891A	(2S)-SB02024	Inhibitor	/	Unkown
HY-132267S	N-Nitrosodibenzylamine-d4	Inhibitor	/	Unkown
HY-172154	SSB-2548		/	Unkown
HY-RS13804	SSB Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W703958	N-Nitrosodibenzylamine-d10		/	Unkown
HY-RS17122	Ssb Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23567	Ssb Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W159870	N-Nitrosodibenzylamine	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ssb	NCBI	NCBI:6741

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