2. Gene
  3. Esrp1 - epithelial splicing regulatory protein 1 Gene

Esrp1 - epithelial splicing regulatory protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rbm35a; A630065D16; 2210008M09Rik

Gene ID: 207920 | Gene type: protein coding

About Esrp1

Summary

Predicted to enable mRNA binding activity. Involved in regulation of RNA splicing and regulation of inner ear auditory receptor cell fate specification. Acts upstream of or within alternative mRNA splicing, via spliceosome; morphogenesis of a branching epithelium; and positive regulation of epithelial cell proliferation. Predicted to be located in nuclear body. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; branchial arch; extraembryonic component; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 109. Orthologous to human ESRP1 (epithelial splicing regulatory protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Esrp1 Products(3)

mRNA Protein Name
NM_001290383.1 NP_001277312.1 epithelial splicing regulatory protein 1 isoform 2
NM_001347052.1 NP_001333981.1 epithelial splicing regulatory protein 1 isoform 3
NM_194055.3 NP_918944.2 epithelial splicing regulatory protein 1 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within alternative mRNA splicing, via spliceosome IGI
IGI: Inferred from genetic interaction
26371508 MGI
acts upstream of or within branching involved in salivary gland morphogenesis IGI
IGI: Inferred from genetic interaction
26371508 MGI
acts upstream of epithelial cell proliferation IGI
IGI: Inferred from genetic interaction
26371508 MGI
acts upstream of or within epithelial tube branching involved in lung morphogenesis IGI
IGI: Inferred from genetic interaction
26371508 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IGI
IGI: Inferred from genetic interaction
26371508 MGI
involved in regulation of RNA splicing IMP
IMP: Inferred from mutant phenotype
29107558 MGI
involved in regulation of inner ear auditory receptor cell fate specification IMP
IMP: Inferred from mutant phenotype
29107558 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

epithelial splicing regulatory protein 1

RNA binding motif protein 35A

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04535 ESRP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20015 Esrp1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26518 Esrp1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Esrp1 NCBI NCBI:54845