2. Gene
  3. Sumo3 - small ubiquitin-like modifier 3 Gene

Sumo3 - small ubiquitin-like modifier 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SMT3A; SUMO-3; Smt3h1; D10Ertd345e; 2810014B19Rik

Gene ID: 20610 | Gene type: protein coding

About Sumo3

Summary

This gene encodes a member of the small ubiquitin-like modifier family. The encoded protein may regulate a variety of proteins in many pathways via a post-translational modification, known as SUMOylation. This activity may play a role in a wide variety of cellular processes, including nuclear transport, DNA replication and repair, Mitosis, transcriptional regulation, and signal transduction. Disruption of some of these processes has been associated with cerebral ischemia, neural dysfunction, and heart disease. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Sumo3 Products(4)

mRNA Protein Name
NM_001301671.1 NP_001288600.1 small ubiquitin-related modifier 3 isoform 2
NM_001301672.1 NP_001288601.1 small ubiquitin-related modifier 3 isoform 3
NM_001301673.1 NP_001288602.1 small ubiquitin-related modifier 3 isoform 4
NM_019929.4 NP_064313.1 small ubiquitin-related modifier 3 isoform 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables SUMO transferase activity IDA
IDA: Inferred from direct assay
15767674 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
18644859 MGI
acts upstream of or within protein localization to nucleus IDA
IDA: Inferred from direct assay
18644859 MGI
acts upstream of or within protein sumoylation IDA
IDA: Inferred from direct assay
15767674 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31749687 MGI
located in nuclear body IDA
IDA: Inferred from direct assay
18644859 MGI
is active in postsynaptic cytosol IDA
IDA: Inferred from direct assay
31749687 MGI
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
31749687 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

small ubiquitin-related modifier 3

SMT3 suppressor of mif two 3 homolog 3

ubiquitin-like protein SMT3A

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14027 SUMO3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21773 Sumo3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sumo3 NCBI NCBI:6612