2. Gene
  3. Sms - spermine synthase Gene

Sms - spermine synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gy; gyro; SPMSY; SpmST

Gene ID: 20603 | Gene type: protein coding

About Sms

Summary

Predicted to enable spermine synthase activity. Acts upstream of or within spermine metabolic process. Is expressed in several structures, including central nervous system; ganglia; limb; respiratory system; and tooth. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Snyder type. Orthologous to human SMS (spermine synthase). [provided by Alliance of Genome Resources, Apr 2022]

Sms Products(2)

mRNA Protein Name
NM_001359185.1 NP_001346114.1 spermine synthase isoform 2
NM_009214.4 NP_033240.3 spermine synthase isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within spermine metabolic process IMP
IMP: Inferred from mutant phenotype
9467015 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spermine synthase

spermidine aminopropyltransferase

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0036 Octreotide 99.87% Unkown
HY-17365 Octreotide acetate Agonist 99.97% Unkown
HY-P0036B Octreotide pamoate / Unkown
Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-163541 SMS121 Inhibitor 99.06% Unkown
HY-114307 Ly93 Inhibitor 99.85% Unkown
HY-N8518 Malabaricone C 99.61% Unkown
HY-102041 SMS2-IN-1 Inhibitor 98.04% Unkown
HY-19625 MCB-613 Inducer 99.64% Unkown
HY-135642 SMS1-IN-1 Inhibitor 99.44% Unkown
HY-112713 SMS2-IN-2 Inhibitor 98.0% Unkown
HY-165136 Sphingomyelins, milk 99.20% Unkown
HY-RS13454 SMS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-171160 WYFA-15 Inhibitor 98.77% Unkown
HY-139995 Spermine Prodrug-1 / Unkown
HY-150559 SMS2-IN-3 Inhibitor / Unkown
HY-157730 2-Myristyldistearin / Unkown
HY-RS11624 RAI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P0036S2 Octreotide-d8 / Unkown
HY-P0036S3 Octreotide-13C9,15N / Unkown
HY-P0036S4 Octreotide-d8 acetate / Unkown
HY-RS17402 Sms Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23857 Sms Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sms NCBI NCBI:6611