Ncor2 - nuclear receptor co-repressor 2 Gene

Mus musculus

Also known as SMRT; N-CoR; SMRTe

Gene ID: 20602 | Gene type: protein coding

About Ncor2

Summary

Enables chromatin binding activity; sequence-specific DNA binding activity; and transcription corepressor activity. Acts upstream of or within several processes, including animal organ development; negative regulation of fat cell differentiation; and positive regulation of protein deacetylation. Located in nuclear body. Part of histone deacetylase complex. Is expressed in several structures, including branchial arch; central nervous system; limb; retina layer; and tooth. Used to study myelofibrosis. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human NCOR2 (nuclear receptor corepressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ncor2 Products(3)

mRNA	Protein	Name
NM_001253904.1	NP_001240833.1	nuclear receptor corepressor 2 isoform 2
NM_001253905.1	NP_001240834.1	nuclear receptor corepressor 2 isoform 3
NM_011424.3	NP_035554.3	nuclear receptor corepressor 2 isoform 1

Protein Preferred Names

Protein Names

nuclear receptor corepressor 2

N-CoR2	T3 receptor-associating factor
TRAC	silencing mediator of retinoic acid and thyroid hormone receptor
silencing mediator of retinoid acid and thyroid hormone receptor	thyroid-, retinoic-acid-receptor-associated corepressor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09097	NCOR2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19464	Ncor2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25957	Ncor2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ncor2	NCBI	NCBI:9612

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