2. Gene
  3. Slc7a5 - solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 Gene

Slc7a5 - solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TA1; LAT1; 4F2LC; Gm42049; D0H16S474E

Gene ID: 20539 | Gene type: protein coding

About Slc7a5

Summary

Enables L-amino acid transmembrane transporter activity. Acts upstream of or within L-amino acid transport. Predicted to be located in several cellular components, including basolateral plasma membrane; external side of apical plasma membrane; and microvillus membrane. Predicted to be integral component of membrane. Predicted to be part of amino acid transport complex. Is expressed in several structures, including central nervous system; cochlea; early conceptus; incisor; and limb. Used to study autism spectrum disorder. Orthologous to human SLC7A5 (solute carrier family 7 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc7a5 Products(1)

mRNA Protein Name
NM_011404.3 NP_035534.2 large neutral amino acids transporter small subunit 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables L-amino acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
15659399 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9915839 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within L-amino acid transport IDA
IDA: Inferred from direct assay
15659399 MGI
involved in L-leucine transport IDA
IDA: Inferred from direct assay
9915839 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
9915839 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

large neutral amino acids transporter small subunit 1

4F2 LC

4F2 light chain

L-type amino acid transporter 1

solute carrier family 7 member 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120139 KMH-233 Inhibitor 99.75% Unkown
HY-RS13331 SLC7A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17279 Slc7a5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23734 Slc7a5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc7a5 NCBI NCBI:8140