Clpb - ClpB caseinolytic peptidase B Gene

Mus musculus

Also known as Skd3

Gene ID: 20480 | Gene type: protein coding

About Clpb

Summary

Predicted to enable ATP hydrolysis activity. Predicted to be involved in RIG-I signaling pathway; Antiviral innate immune response; and cellular response to heat. Located in mitochondrion. Is expressed in several structures, including central nervous system; inner cell mass; limb; paravertebral ganglion; and retina. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria with cataracts, neurologic involvement and neutropenia. Orthologous to human CLPB (caseinolytic mitochondrial matrix peptidase chaperone subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Clpb Products(2)

mRNA	Protein	Name
NM_001363991.1	NP_001350920.1	caseinolytic peptidase B protein homolog isoform 2 precursor
NM_009191.4	NP_033217.1	caseinolytic peptidase B protein homolog isoform 1 precursor

Protein Preferred Names

Protein Names

caseinolytic peptidase B protein homolog

ClpB caseinolytic peptidase B homolog	suppressor of K+ transport defect 3
suppressor of potassium transport defect 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-150166	ClpB-IN-1	Inhibitor	98.00%	Unkown
HY-W016969	2-Undecanone	Inhibitor	98.96%	Unkown
HY-RS02830	CLPB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22124	Clpb Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Clpb	NCBI	NCBI:81570

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