1. Gene
  2. Six1 - sine oculis-related homeobox 1 Gene

Six1 - sine oculis-related homeobox 1 Gene

Mus musculus
Gene ID: 20471 | Gene type: protein coding

About Six1

Summary

Enables DNA-binding transcription factor activity; chromatin binding activity; and sequence-specific DNA binding activity. Involved in several processes, including animal organ development; myotome development; and positive regulation of morphogenesis of an epithelium. Acts upstream of or within several processes, including animal organ development; positive regulation of cell population proliferation; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; limb; and sensory organ. Used to study branchiootorenal syndrome. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 23; branchiootorenal syndrome; and nephroblastoma. Orthologous to human SIX1 (SIX homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Six1 Products(1)

mRNA Protein Name
NM_009189.3 NP_033215.2 homeobox protein SIX1
Protein Preferred Names Protein Names

homeobox protein SIX1

sine oculis homeobox homolog 1

sine oculis-related homeobox 1 homolog

Orthologs Information

Species Symbol Source ID
Homo sapiens Six1 NCBI NCBI:6495