2. Gene
  3. Sin3b - transcriptional regulator, SIN3B (yeast) Gene

Sin3b - transcriptional regulator, SIN3B (yeast) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2810430C10Rik

Gene ID: 20467 | Gene type: protein coding

About Sin3b

Summary

Enables chromatin binding activity and transcription corepressor activity. Involved in cardiac muscle tissue development; negative regulation of transcription, DNA-templated; and skeletal muscle tissue development. Located in several cellular components, including autosome; nucleus; and sex chromosome. Is expressed in several structures, including central nervous system; dorsal root ganglion; eye; genitourinary system; and paraxial mesenchyme. Orthologous to human SIN3B (SIN3 transcription regulator family member B). [provided by Alliance of Genome Resources, Apr 2022]

Sin3b Products(2)

mRNA Protein Name
NM_001113248.2 NP_001106719.1 paired amphipathic helix protein Sin3b isoform 2
NM_009188.4 NP_033214.2 paired amphipathic helix protein Sin3b isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
16103876 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8521822 MGI
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
7889570 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cardiac muscle tissue development IDA
IDA: Inferred from direct assay
10620510 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
7889570 MGI
involved in skeletal muscle tissue development IDA
IDA: Inferred from direct assay
10620510 MGI
Cellular Component GO Annotation Evidence Reference Source
located in X chromosome IDA
IDA: Inferred from direct assay
16787967 MGI
located in XY body IDA
IDA: Inferred from direct assay
16787967 MGI
located in Y chromosome IDA
IDA: Inferred from direct assay
16787967 MGI
located in autosome IDA
IDA: Inferred from direct assay
16787967 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
10620510 MGI
located in nucleus IDA
IDA: Inferred from direct assay
8649810 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paired amphipathic helix protein Sin3b

SIN3 homolog B, transcription regulator

histone deacetylase complex subunit Sin3b

transcriptional corepressor Sin3b

transcriptional regulator, SIN3 yeast homolog B

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12926 SIN3B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21756 Sin3b Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28274 Sin3b Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sin3b NCBI NCBI:23309