2. Gene
  3. St3gal1 - ST3 beta-galactoside alpha-2,3-sialyltransferase 1 Gene

St3gal1 - ST3 beta-galactoside alpha-2,3-sialyltransferase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Siat4; Siat4a; ST3GalI; St3gal-1; 5330418N22Rik

Gene ID: 20442 | Gene type: protein coding

About St3gal1

Summary

Enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Involved in several processes, including ganglioside biosynthetic process via lactosylceramide; memory B cell differentiation; and negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process. Acts upstream of or within protein glycosylation and protein phosphorylation. Predicted to be located in Golgi medial cisterna membrane; Golgi trans cisterna membrane; and trans-Golgi network membrane. Is expressed in several structures, including alimentary system; ear; hemolymphoid system; integumental system; and nervous system. Orthologous to human ST3GAL1 (ST3 beta-galactoside alpha-2,3-sialyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

St3gal1 Products(4)

mRNA Protein Name
NM_001412635.1 NP_001399564.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
NM_001412636.1 NP_001399565.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
NM_001412637.1 NP_001399566.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
NM_009177.5 NP_033203.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IDA
IDA: Inferred from direct assay
8144500 MGI
enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IMP
IMP: Inferred from mutant phenotype
12068010 MGI
Biological Process GO Annotation Evidence Reference Source
involved in ganglioside biosynthetic process via lactosylceramide IDA
IDA: Inferred from direct assay
8144500 MGI
involved in memory B cell differentiation IMP
IMP: Inferred from mutant phenotype
10755614 MGI
involved in negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process IMP
IMP: Inferred from mutant phenotype
10755614 MGI
acts upstream of or within protein glycosylation IDA
IDA: Inferred from direct assay
8375377 MGI
acts upstream of or within protein glycosylation IMP
IMP: Inferred from mutant phenotype
12068010 MGI
acts upstream of or within protein phosphorylation IDA
IDA: Inferred from direct assay
9184827 MGI
involved in protein sialylation IDA
IDA: Inferred from direct assay
8144500 MGI
involved in protein sialylation IMP
IMP: Inferred from mutant phenotype
10755614 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

CMP-N-acetylneuraminate: [beta-galactosidase alpha-2,3] sialytransferase

Gal beta1,3 GalNAc alpha2,3 sialyltransferase

SIAT4-A

ST3GAL-I sialyltransferase

ST3Gal I

ST3GalA.1

ST3O

alpha 2,3-ST 1

beta-galactoside alpha-2,3-sialyltransferase 1

gal-NA

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-E70298 ST3 β-Gal α-2,3-Sialyltransferase 1 / Unkown
HY-RS13846 ST3GAL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20651 St3gal1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27162 St3gal1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens St3gal1 NCBI NCBI:6482