2. Gene
  3. Sord - sorbitol dehydrogenase Gene

Sord - sorbitol dehydrogenase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SDH; XDH; Sdh1; Sdh-1; Sodh-1

Gene ID: 20322 | Gene type: protein coding

About Sord

Summary

Enables L-iditol 2-dehydrogenase activity. Involved in flagellated sperm motility. Acts upstream of or within sorbitol metabolic process. Located in mitochondrion and motile cilium. Is expressed in several structures, including alimentary system; limb; liver; metanephros; and nervous system. Used to study cataract. Orthologous to human SORD (sorbitol dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Sord Products(1)

mRNA Protein Name
NM_146126.4 NP_666238.1 sorbitol dehydrogenase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables D-sorbitol dehydrogenase (acceptor) activity IDA
IDA: Inferred from direct assay
6626150 MGI
enables D-sorbitol dehydrogenase (acceptor) activity IMP
IMP: Inferred from mutant phenotype
9403062 MGI
enables D-xylulose reductase activity IDA
IDA: Inferred from direct assay
38160 MGI
enables L-iditol 2-dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
722274 MGI
enables L-iditol 2-dehydrogenase (NAD+) activity IMP
IMP: Inferred from mutant phenotype
9403062 MGI
Biological Process GO Annotation Evidence Reference Source
involved in D-glucuronate catabolic process to D-xylulose 5-phosphate IDA
IDA: Inferred from direct assay
38160 MGI
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
18799757 MGI
involved in fructose biosynthetic process IDA
IDA: Inferred from direct assay
18799757 MGI
involved in fructose biosynthetic process IMP
IMP: Inferred from mutant phenotype
9604875 MGI
acts upstream of or within sorbitol metabolic process IDA
IDA: Inferred from direct assay
722274 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
38160 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
18799757 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
18799757 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sorbitol dehydrogenase

L-iditol 2-dehydrogenase

polyol dehydrogenase

sorbitol dehydrogenase 1

xylitol dehydrogenase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13573 SORD Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18973 Sord Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25462 Sord Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sord NCBI NCBI:6652