2. Gene
  3. Sag - S-antigen, retina and pineal gland (arrestin) Gene

Sag - S-antigen, retina and pineal gland (arrestin) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Arr1; Irbp; arrestin; A930001K18Rik

Gene ID: 20215 | Gene type: protein coding

About Sag

Summary

Enables opsin binding activity and phosphoprotein binding activity. Predicted to be involved in G protein-coupled receptor internalization. Located in photoreceptor inner segment and photoreceptor outer segment. Is expressed in eye and retina outer nuclear layer. Human ortholog(s) of this gene implicated in Oguchi disease-1; hereditary night blindness; and retinitis pigmentosa 47. Orthologous to human SAG (S-antigen visual Arrestin). [provided by Alliance of Genome Resources, Apr 2022]

Sag Products(1)

mRNA Protein Name
NM_009118.2 NP_033144.1 S-arrestin
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables opsin binding IDA
IDA: Inferred from direct assay
12486395 MGI
enables phosphoprotein binding IDA
IDA: Inferred from direct assay
12486395 MGI
Cellular Component GO Annotation Evidence Reference Source
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
22869374 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
22869374 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

S-arrestin

48 kDa protein

S-AG

arrestin 1

retinal S-antigen

rod arrestin

rod photoreceptor arrestin

visual arrestin 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12848 SAG Agonist 99.79% Unkown
HY-12848B SAG hydrochloride Agonist 99.91% Unkown
HY-12848C SAG dihydrochloride Agonist 99.31% Unkown
HY-117771 DO34 99.30% Unkown
HY-124899 Hh-Ag1.5 Agonist 99.90% Unkown
HY-B0633C Hyaluronic acid (Mw:1000-2000Da) / Unkown
HY-157993 SAG-524 Inhibitor 98.50% Unkown
HY-12848R SAG (Standard) Agonist / Unkown
HY-163455 pan-HCN-IN-1 Inhibitor / Unkown
HY-RS12096 RNF7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-110240 IHR-1 Antagonist 98.05% Unkown
HY-12848A (Rac)-SAG Agonist / Unkown
HY-12848S SAG-d3 Inhibitor 99.85% Unkown
HY-N15152 Isoaesculioside D / Unkown
HY-RS03820 DMBT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12415 SAG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-12848G SAG (GMP) Agonist / Unkown
HY-RS16512 Sag Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22944 Sag Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sag NCBI NCBI:6295