2. Gene
  3. Polr2a - polymerase (RNA) II (DNA directed) polypeptide A Gene

Polr2a - polymerase (RNA) II (DNA directed) polypeptide A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rpb1; 220kDa; Rpo2-1

Gene ID: 20020 | Gene type: protein coding

About Polr2a

Summary

Enables core promoter sequence-specific DNA binding activity. Predicted to be involved in DNA-templated transcription, termination; positive regulation of RNA splicing; and transcription by RNA polymerase II. Located in euchromatin and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human POLR2A (RNA polymerase II subunit A). [provided by Alliance of Genome Resources, Apr 2022]

Polr2a Products(1)

mRNA Protein Name
NM_001291068.1 NP_001277997.1 DNA-directed RNA polymerase II subunit RPB1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
15601870 MGI
enables core promoter sequence-specific DNA binding IDA
IDA: Inferred from direct assay
22723415 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8692929 MGI
Cellular Component GO Annotation Evidence Reference Source
located in euchromatin IDA
IDA: Inferred from direct assay
22723415 MGI
located in nucleus IDA
IDA: Inferred from direct assay
26346254 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerase II subunit RPB1

DNA-directed RNA polymerase II subunit A

DNA-directed RNA polymerase III largest subunit

RNA polymerase II 1

RNA polymerase II subunit B1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-135646 Eleutheroside B1 Inhibitor 98.73% Unkown
HY-RS10842 POLR2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19802 Polr2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26298 Polr2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr2a NCBI NCBI:5430