2. Gene
  3. Polr1b - polymerase (RNA) I polypeptide B Gene

Polr1b - polymerase (RNA) I polypeptide B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as RPA2; 128kDa; RPA116; RPA135; Rpo1-2; D630020H17Rik

Gene ID: 20017 | Gene type: protein coding

About Polr1b

Summary

Predicted to enable several functions, including DNA binding activity; metal ion binding activity; and ribonucleoside binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Acts upstream of or within embryo implantation; nucleologenesis; and rRNA transcription. Located in chromosome and nucleolus. Part of RNA polymerase I complex. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Orthologous to human POLR1B (RNA polymerase I subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Polr1b Products(1)

mRNA Protein Name
NM_009086.2 NP_033112.2 DNA-directed RNA polymerase I subunit RPA2
Protein Preferred Names Protein Names

DNA-directed RNA polymerase I subunit RPA2

DNA-directed RNA polymerase I 135 kDa polypeptide

DNA-directed RNA polymerase I 135kDa polypeptide

RNA polymerase 1-2, 128 kDa subunit

RNA polymerase I subunit 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10838 POLR1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21910 Polr1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr1b NCBI NCBI:84172