2. Gene
  3. Rfc1 - replication factor C (activator 1) 1 Gene

Rfc1 - replication factor C (activator 1) 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Recc1; 140kDa; Alp145; RFC140

Gene ID: 19687 | Gene type: protein coding

About Rfc1

Summary

Predicted to enable DNA binding activity; DNA clamp unloader activity; and protein domain specific binding activity. Predicted to be involved in DNA clamp unloading; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; genitourinary system; and retina. Human ortholog(s) of this gene implicated in West Nile fever. Orthologous to human RFC1 (replication factor C subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Rfc1 Products(3)

mRNA Protein Name
NM_001347357.1 NP_001334286.1 replication factor C subunit 1 isoform 1
NM_001347358.1 NP_001334287.1 replication factor C subunit 1 isoform 3
NM_011258.2 NP_035388.2 replication factor C subunit 1 isoform 2
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
11555636 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

replication factor C subunit 1

A1 140 kDa subunit

A1-P145

ISRE-binding protein

RF-C 140 kDa subunit

activator 1 140 kDa subunit

activator 1 large subunit

activator 1 subunit 1

differentiation-specific element-binding protein

replication factor C 1

replication factor C 140 kDa

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11865 RFC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13047 SLC19A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22297 Rfc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28820 Rfc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rfc1 NCBI NCBI:5981