2. Gene
  3. Cavin1 - caveolae associated 1 Gene

Cavin1 - caveolae associated 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ptrf; Cavin; Cav-p60; 2310075E07Rik

Gene ID: 19285 | Gene type: protein coding

About Cavin1

Summary

Enables rRNA primary transcript binding activity. Involved in positive regulation of cell motility; protein secretion; and transcription, DNA-templated. Acts upstream of or within termination of RNA polymerase I transcription. Located in caveola; endoplasmic reticulum; and nucleus. Is expressed in several structures, including genitourinary system and sensory organ. Used to study congenital generalized lipodystrophy type 4 and pulmonary hypertension. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 4. Orthologous to human CAVIN1 (caveolae associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Cavin1 Products(2)

mRNA Protein Name
NM_001359105.1 NP_001346034.1 caveolae-associated protein 1 isoform 2
NM_008986.2 NP_033012.1 caveolae-associated protein 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10589839 MGI
enables rRNA primary transcript binding IDA
IDA: Inferred from direct assay
9582279 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cell motility IMP
IMP: Inferred from mutant phenotype
25514038 MGI
involved in protein secretion IMP
IMP: Inferred from mutant phenotype
30188967 MGI
involved in rRNA transcription IMP
IMP: Inferred from mutant phenotype
27528195 MGI
acts upstream of or within termination of RNA polymerase I transcription IDA
IDA: Inferred from direct assay
9582279 MGI
involved in termination of RNA polymerase I transcription IDA
IDA: Inferred from direct assay
9582279 MGI
involved in transcription initiation at RNA polymerase I promoter IDA
IDA: Inferred from direct assay
11139612 MGI
Cellular Component GO Annotation Evidence Reference Source
located in caveola IDA
IDA: Inferred from direct assay
18191225 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
30188967 MGI
located in nucleus IDA
IDA: Inferred from direct assay
25514038 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

caveolae-associated protein 1

cavin-1

polymerase I and transcript release factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01989 CAVIN1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21832 Cavin1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cavin1 NCBI NCBI:284119