2. Gene
  3. Ptpre - protein tyrosine phosphatase, receptor type, E Gene

Ptpre - protein tyrosine phosphatase, receptor type, E Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PTPe; PTPepsilon; RPTPepsilon

Gene ID: 19267 | Gene type: protein coding

About Ptpre

Summary

Enables identical protein binding activity and protein tyrosine Phosphatase activity. Involved in negative regulation of Insulin Receptor signaling pathway and regulation of mast cell activation. Acts upstream of or within transmembrane receptor protein tyrosine Phosphatase signaling pathway. Located in cytoplasm and plasma membrane. Is expressed in midbrain and superior colliculus. Orthologous to human PTPRE (protein tyrosine Phosphatase receptor type E). [provided by Alliance of Genome Resources, Apr 2022]

Ptpre Products(5)

mRNA Protein Name
NM_001316678.1 NP_001303607.1 receptor-type tyrosine-protein phosphatase epsilon isoform a
NM_001316679.1 NP_001303608.1 receptor-type tyrosine-protein phosphatase epsilon isoform b precursor
NM_001316680.1 NP_001303609.1 receptor-type tyrosine-protein phosphatase epsilon isoform c precursor
NM_001316681.1 NP_001303610.1 receptor-type tyrosine-protein phosphatase epsilon isoform d
NM_011212.3 NP_035342.3 receptor-type tyrosine-protein phosphatase epsilon isoform b precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
12861030 MGI
enables protein tyrosine phosphatase activity IDA
IDA: Inferred from direct assay
12861030 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell surface receptor protein tyrosine phosphatase signaling pathway IDA
IDA: Inferred from direct assay
12861030 MGI
involved in negative regulation of insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
18006633 MGI
involved in regulation of mast cell activation IMP
IMP: Inferred from mutant phenotype
19508371 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
18006633 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
18006633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor-type tyrosine-protein phosphatase epsilon

R-PTP-epsilon

protein-tyrosine phosphatase epsilon

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11437 PTPRE Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21706 Ptpre Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptpre NCBI NCBI:5791