2. Gene
  3. Lamc2 - laminin subunit gamma 2 Gene

Lamc2 - laminin subunit gamma 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 192362 | Gene type: protein coding

About Lamc2

Summary

Predicted to enable heparin binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including neuron projection development; positive regulation of cell migration; and positive regulation of cell population proliferation. Located in several cellular components, including cell cortex; extracellular space; and perinuclear region of cytoplasm. Part of laminin-2 complex. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Orthologous to human LAMC2 (laminin subunit gamma 2). [provided by Alliance of Genome Resources, Apr 2022]

Lamc2 Products(1)

mRNA Protein Name
NM_001100640.2 NP_001094110.1 laminin subunit gamma-2 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in cell cortex IDA
IDA: Inferred from direct assay
16409251 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
16409251 RGD
part of laminin-2 complex IDA
IDA: Inferred from direct assay
9417868 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
16409251 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

laminin subunit gamma-2

lamimin, gamma 2

laminin, gamma 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07507 LAMC2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20979 Lamc2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27496 Lamc2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lamc2 NCBI NCBI:3918