2. Gene
  3. Ptdss1 - phosphatidylserine synthase 1 Gene

Ptdss1 - phosphatidylserine synthase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PSS-1; mKIAA0024

Gene ID: 19210 | Gene type: protein coding

About Ptdss1

Summary

Enables L-serine-phosphatidylcholine phosphatidyltransferase activity and L-serine-phosphatidylethanolamine phosphatidyltransferase activity. Predicted to be involved in phosphatidylserine biosynthetic process. Predicted to act upstream of or within phospholipid biosynthetic process. Located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in Lenz-Majewski hyperostotic dwarfism. Orthologous to human PTDSS1 (phosphatidylserine synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ptdss1 Products(1)

mRNA Protein Name
NM_008959.3 NP_032985.2 phosphatidylserine synthase 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables L-serine-phosphatidylcholine phosphatidyltransferase activity IDA
IDA: Inferred from direct assay
10432300 MGI
enables L-serine-phosphatidylcholine phosphatidyltransferase activity IMP
IMP: Inferred from mutant phenotype
9516423 MGI
enables L-serine-phosphatidylethanolamine phosphatidyltransferase activity IDA
IDA: Inferred from direct assay
10432300 MGI
enables L-serine-phosphatidylethanolamine phosphatidyltransferase activity IMP
IMP: Inferred from mutant phenotype
9516423 MGI
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
10938271 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylserine synthase 1

PtdSer Synthase-1

ptdSer synthase 1

serine-exchange enzyme I

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-158145 DS55980254 Inhibitor 99.65% Unkown
HY-157562 DS68591889 99.18% Unkown
HY-RS11361 PTDSS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20585 Ptdss1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27093 Ptdss1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptdss1 NCBI NCBI:9791