2. Gene
  3. Pnmt - phenylethanolamine-N-methyltransferase Gene

Pnmt - phenylethanolamine-N-methyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pent

Gene ID: 18948 | Gene type: protein coding

About Pnmt

Summary

Predicted to enable phenylethanolamine N-methyltransferase activity. Predicted to be involved in epinephrine biosynthetic process and norepinephrine metabolic process. Predicted to act upstream of or within Catecholamine biosynthetic process and methylation. Predicted to be located in several cellular components, including axon; dendrite; and perikaryon. Predicted to be active in cytosol. Is expressed in several structures, including adrenal gland; brain; gonad; and metanephros. Human ortholog(s) of this gene implicated in Alzheimer's disease; hypertension; and multiple sclerosis. Orthologous to human PNMT (phenylethanolamine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Pnmt Products(1)

mRNA Protein Name
NM_008890.3 NP_032916.1 phenylethanolamine N-methyltransferase
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables phenylethanolamine N-methyltransferase activity IDA
IDA: Inferred from direct assay
17698731 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phenylethanolamine N-methyltransferase

PNMTase

noradrenaline N-methyltransferase

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107398 1-(2,3-Dichlorophenyl)ethanamine hydrochloride Inhibitor 99.93% Unkown
HY-113969 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline / Unkown
HY-149389 PNMT-IN-1 Inhibitor / Unkown
HY-RS10785 PNMT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20796 Pnmt Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27310 Pnmt Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pnmt NCBI NCBI:5409
Canis lupus familiaris Pnmt NCBI