2. Gene
  3. Plod1 - procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 Gene

Plod1 - procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Lh1; Plod; 2410042F05Rik

Gene ID: 18822 | Gene type: protein coding

About Plod1

Summary

Predicted to enable several functions, including L-ascorbic acid binding activity; ferrous iron binding activity; and procollagen-lysine 5-dioxygenase activity. Predicted to be involved in epidermis development and peptidyl-lysine hydroxylation. Located in collagen-containing extracellular matrix. Part of catalytic complex. Is expressed in several structures, including alimentary system; brain; integumental system; sensory organ; and skeleton. Used to study Ehlers-Danlos syndrome. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome kyphoscoliotic type 1. Orthologous to human PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Plod1 Products(1)

mRNA Protein Name
NM_011122.3 NP_035252.1 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
27119146 MGI
Cellular Component GO Annotation Evidence Reference Source
part of catalytic complex IMP
IMP: Inferred from mutant phenotype
27119146 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10728 PLOD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21027 Plod1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27544 Plod1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plod1 NCBI NCBI:5351