2. Gene
  3. Pld3 - phospholipase D family, member 3 Gene

Pld3 - phospholipase D family, member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sam-9

Gene ID: 18807 | Gene type: protein coding

About Pld3

Summary

Enables single-stranded DNA 5'-3' exodeoxyribonuclease activity. Involved in regulation of cytokine production involved in inflammatory response. Located in late endosome membrane and lysosomal membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 46. Orthologous to human PLD3 (Phospholipase D family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Pld3 Products(2)

mRNA Protein Name
NM_001317355.1 NP_001304284.1 5'-3' exonuclease PLD3
NM_011116.2 NP_035246.1 5'-3' exonuclease PLD3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
NOT enables phospholipase D activity IDA
IDA: Inferred from direct assay
9813063 MGI
enables single-stranded DNA 5'-3' DNA exonuclease activity IDA
IDA: Inferred from direct assay
30111894 MGI
Biological Process GO Annotation Evidence Reference Source
involved in regulation of cytokine production involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
22102906 MGI
Cellular Component GO Annotation Evidence Reference Source
located in late endosome membrane IDA
IDA: Inferred from direct assay
28128235 MGI
located in lysosomal membrane IDA
IDA: Inferred from direct assay
28128235 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5'-3' exonuclease PLD3

PLD 3

choline phosphatase 3

phosphatidylcholine-hydrolyzing phospholipase D3

phospholipase D3

schwannoma-associated protein 9

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10672 PLD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20795 Pld3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27309 Pld3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pld3 NCBI NCBI:23646