2. Gene
  3. Pld2 - phospholipase D2 Gene

Pld2 - phospholipase D2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PLD1C

Gene ID: 18806 | Gene type: protein coding

About Pld2

Summary

This gene is a member of the Phospholipase D (PLD) superfamily. The encoded protein catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. Phosphatidic acid is an essential intracellular lipid second messenger for many signaling pathways and has been implicated in a variety of physiological processes including cytoskeletal organization and cell proliferation. A similar gene in human may also function as a guanine nucleotide exchange factor (GEF) for the small GTPase Rac2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

Pld2 Products(4)

mRNA Protein Name
NM_001302475.1 NP_001289404.1 phospholipase D2 isoform 1
NM_001302476.1 NP_001289405.1 phospholipase D2 isoform 3
NM_001361935.1 NP_001348864.1 phospholipase D2 isoform 4
NM_008876.3 NP_032902.1 phospholipase D2 isoform 2
Protein Preferred Names Protein Names

phospholipase D2

choline phosphatase 2

phosphatidylcholine-hydrolyzing phospholipase D2

Related Agents

Pre-clinical Phase
Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12807 FIPI Inhibitor 99.49% Unkown
HY-121983 CAY10594 Inhibitor 98.95% Unkown
HY-101293 VU0359595 Inhibitor 98.06% Unkown
HY-119093 Halopemide 99.65% Unkown
HY-150412 VU0364739 Inhibitor 99.33% Unkown
HY-116165 ML-298 Inhibitor ≥98.0% Unkown
HY-155342 A3373 Inhibitor 99.06% Unkown
HY-114095 BML-280 Inhibitor 99.64% Unkown
HY-108616 VU 0364739 hydrochloride Inhibitor / Unkown
HY-12807A FIPI hydrochloride Inhibitor / Unkown
HY-108612A VU0155069 hydrochloride Inhibitor / Unkown
HY-124305 ML395 / Unkown
HY-142980 Dioleoylphosphatidylglycerol / Unkown
HY-155343 A4333 Inhibitor / Unkown
HY-RS10671 PLD2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19152 Pld2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25641 Pld2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pld2 NCBI NCBI:5338