2. Gene
  3. Etv4 - ets variant 4 Gene

Etv4 - ets variant 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pea3; Pea-3

Gene ID: 18612 | Gene type: protein coding

About Etv4

Summary

Enables DNA binding activity. Involved in positive regulation of gene expression. Acts upstream of or within several processes, including branching involved in mammary gland duct morphogenesis; motor neuron axon guidance; and negative regulation of mammary gland epithelial cell proliferation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; sensory organ; and urinary system. Orthologous to human ETV4 (ETS variant transcription factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Etv4 Products(3)

mRNA Protein Name
NM_001316365.1 NP_001303294.1 ETS translocation variant 4 isoform 1
NM_001316366.1 NP_001303295.1 ETS translocation variant 4 isoform 3
NM_008815.3 NP_032841.2 ETS translocation variant 4 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
12527199 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within branching involved in mammary gland duct morphogenesis IDA
IDA: Inferred from direct assay
12871699 MGI
acts upstream of or within branching involved in mammary gland duct morphogenesis IMP
IMP: Inferred from mutant phenotype
18977342 MGI
acts upstream of or within motor neuron axon guidance IMP
IMP: Inferred from mutant phenotype
12372283 MGI
acts upstream of or within negative regulation of mammary gland epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
18977342 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
15466854 MGI
acts upstream of or within positive regulation of DNA-templated transcription IPI
IPI: Inferred from physical interaction
15466854 MGI
involved in positive regulation of gene expression IDA
IDA: Inferred from direct assay
15253939 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
22014525 MGI
acts upstream of or within stem cell differentiation IMP
IMP: Inferred from mutant phenotype
18977342 MGI
acts upstream of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
22014525 MGI
Cellular Component GO Annotation Evidence Reference Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
10482234 MGI
located in nucleus IDA
IDA: Inferred from direct assay
25512490 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ETS translocation variant 4

ETS variant protein 4

POLYOMAVIRUS ENHANCER ACTIVATOR 3 (PEA3 PROTEIN) (ETS TRANSLOCATION VARIANT 4)

ets variant gene 4 (E1A enhancer binding protein, E1AF)

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04567 ETV4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22164 Etv4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Etv4 NCBI NCBI:2118