Pdha1 - pyruvate dehydrogenase E1 alpha 1 Gene

Mus musculus

Also known as Pdha-1

Gene ID: 18597 | Gene type: protein coding

About Pdha1

Summary

Enables pyruvate dehydrogenase (NAD+) activity. Acts upstream of or within mitochondrial acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Is expressed in several structures, including alimentary system; metanephros; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHA1 (pyruvate dehydrogenase E1 subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdha1 Products(1)

mRNA	Protein	Name
NM_008810.3	NP_032836.1	pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial precursor

Protein Preferred Names

Protein Names

pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

PDHE1-A type I

pyruvate dehydrogenase E1alpha subunit

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10261	PDHA1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS17710	Pdha1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24175	Pdha1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pdha1	NCBI	NCBI:5160

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