2. Gene
  3. Pdcd6 - programmed cell death 6 Gene

Pdcd6 - programmed cell death 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PS2; Alg2; MA-3; alg-2

Gene ID: 18570 | Gene type: protein coding

About Pdcd6

Summary

Enables calcium-dependent protein binding activity; metal ion binding activity; and protein homodimerization activity. Involved in response to calcium ion. Acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process and apoptotic process. Located in cytoplasm. Orthologous to human PDCD6 (programmed cell death 6). [provided by Alliance of Genome Resources, Apr 2022]

Pdcd6 Products(2)

mRNA Protein Name
NM_001359996.1 NP_001346925.1 programmed cell death protein 6 isoform 2
NM_011051.3 NP_035181.1 programmed cell death protein 6 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium ion binding IMP
IMP: Inferred from mutant phenotype
17214967 MGI
enables calcium-dependent protein binding IPI
IPI: Inferred from physical interaction
17214967 MGI
enables magnesium ion binding IDA
IDA: Inferred from direct assay
27541325 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11606059 MGI
enables protein dimerization activity IPI
IPI: Inferred from physical interaction
10200558 MGI
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
27541325 MGI
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
10200558 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: Inferred from direct assay
14561754 MGI
acts upstream of or within apoptotic process IDA
IDA: Inferred from direct assay
8560270 MGI
involved in response to calcium ion IDA
IDA: Inferred from direct assay
17214967 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17214967 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

programmed cell death protein 6

ALG-257

PMP41

apoptosis-linked gene 2 protein

probable calcium-binding protein ALG-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10194 PDCD6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10195 PDCD6IP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19469 Pdcd6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25962 Pdcd6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdcd6 NCBI NCBI:10016