2. Gene
  3. Otx1 - orthodenticle homeobox 1 Gene

Otx1 - orthodenticle homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as jv; A730044F23Rik

Gene ID: 18423 | Gene type: protein coding

About Otx1

Summary

This gene encodes a member of the bicoid subfamily of the paired homeobox transcription factor family. The encoded protein is critical to the maintenance and regionalization of the forebrain and midbrain during development. It may also have important functions in sense organ development, pituitary function, and in the regulation of blood cell production. [provided by RefSeq, Jul 2008]

Otx1 Products(1)

mRNA Protein Name
NM_011023.3 NP_035153.1 homeobox protein OTX1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15105370 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within anterior/posterior pattern specification IGI
IGI: Inferred from genetic interaction
15105370 MGI
acts upstream of or within diencephalon morphogenesis IGI
IGI: Inferred from genetic interaction
20816794 MGI
acts upstream of or within forebrain development IGI
IGI: Inferred from genetic interaction
15201224 MGI
acts upstream of or within inner ear morphogenesis IGI
IGI: Inferred from genetic interaction
10225993 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: Inferred from mutant phenotype
10225993 MGI
acts upstream of or within metencephalon development IGI
IGI: Inferred from genetic interaction
20816794 MGI
acts upstream of or within midbrain development IGI
IGI: Inferred from genetic interaction
15201224 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15105370 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein OTX1

orthodenticle homolog 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09879 OTX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20790 Otx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27304 Otx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Otx1 NCBI NCBI:5013