2. Gene
  3. Nfil3 - nuclear factor, interleukin 3, regulated Gene

Nfil3 - nuclear factor, interleukin 3, regulated Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as E4BP4

Gene ID: 18030 | Gene type: protein coding

About Nfil3

Summary

The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses Per1 and Per2 expression and therefore plays a role in the regulation of circadian rhythm. [provided by RefSeq, Feb 2014]

Nfil3 Products(1)

mRNA Protein Name
NM_017373.3 NP_059069.1 nuclear factor interleukin-3-regulated protein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
21460847 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20599664 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to interleukin-4 IDA
IDA: Inferred from direct assay
9798653 MGI
involved in natural killer cell differentiation IMP
IMP: Inferred from mutant phenotype
32190943 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
30555544 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
29653076 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
21460847 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
21460847 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear factor interleukin-3-regulated protein

E4 promoter-binding protein 4

embryo implantation-related NFIL3/E4BP4-like transcription factor

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09252 NFIL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18072 Nfil3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24547 Nfil3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfil3 NCBI NCBI:4783