Ndufa4 - Ndufa4, mitochondrial complex associated Gene

Mus musculus

Also known as MLRQ

Gene ID: 17992 | Gene type: protein coding

About Ndufa4

Summary

Predicted to be involved in positive regulation of cytochrome-c oxidase activity. Located in mitochondrial inner membrane. Part of mitochondrial respiratory chain complex I and mitochondrial respiratory chain complex IV. Is expressed in several structures, including alimentary system; central nervous system; integumental system; metanephros; and sensory organ. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human NDUFA4 (NDUFA4 mitochondrial complex associated). [provided by Alliance of Genome Resources, Apr 2022]

Ndufa4 Products(1)

mRNA	Protein	Name
NM_010886.3	NP_035016.1	cytochrome c oxidase subunit NDUFA4

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	31536960	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of respiratory chain complex IV	IDA IDA: Inferred from direct assay	22902835	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cytochrome c oxidase subunit NDUFA4

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09130	NDUFA4L2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09129	NDUFA4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19794	Ndufa4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26290	Ndufa4 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ndufa4	NCBI	NCBI:4697

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