2. Gene
  3. Ncf4 - neutrophil cytosolic factor 4 Gene

Ncf4 - neutrophil cytosolic factor 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p40phox

Gene ID: 17972 | Gene type: protein coding

About Ncf4

Summary

Predicted to enable phosphatidylinositol-3-phosphate binding activity and superoxide-generating NADPH Oxidase activator activity. Predicted to be involved in superoxide anion generation. Located in cytoplasm. Is expressed in liver; lower urinary tract; stomach; and testis. Human ortholog(s) of this gene implicated in autosomal recessive chronic granulomatous disease cytochrome b-positive type III and rheumatoid arthritis. Orthologous to human NCF4 (neutrophil cytosolic factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Ncf4 Products(4)

mRNA Protein Name
NM_001411421.1 NP_001398350.1 neutrophil cytosol factor 4 isoform 2
NM_001411422.1 NP_001398351.1 neutrophil cytosol factor 4 isoform 1
NM_001411423.1 NP_001398352.1 neutrophil cytosol factor 4 isoform 1
NM_008677.3 NP_032703.2 neutrophil cytosol factor 4 isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
9490028 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15850784 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neutrophil cytosol factor 4

NCF-4

neutrophil NADPH oxidase factor 4

p40-phox

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09079 NCF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20781 Ncf4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27295 Ncf4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncf4 NCBI NCBI:4689