Myf5 - myogenic factor 5 Gene

Mus musculus

Also known as Myf-5; bHLHc2; B130010J22Rik

Gene ID: 17877 | Gene type: protein coding

About Myf5

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; regulation of cell-matrix adhesion; and somitogenesis. Predicted to be located in nucleoplasm. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and skeletal musculature. Orthologous to human MYF5 (myogenic factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Myf5 Products(1)

mRNA	Protein	Name
NM_008656.5	NP_032682.1	myogenic factor 5

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	24361185	MGI
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	22638570	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within camera-type eye development	IMP IMP: Inferred from mutant phenotype	19531352	MGI
acts upstream of or within cartilage condensation	IMP IMP: Inferred from mutant phenotype	8565825	MGI
acts upstream of or within embryonic skeletal system morphogenesis	IMP IMP: Inferred from mutant phenotype	10929709	MGI
acts upstream of or within extracellular matrix organization	IMP IMP: Inferred from mutant phenotype	16554364	MGI
acts upstream of or within muscle organ development	IGI IGI: Inferred from genetic interaction	8587605	MGI
acts upstream of or within muscle organ development	IMP IMP: Inferred from mutant phenotype	8587605	MGI
acts upstream of or within muscle organ morphogenesis	IGI IGI: Inferred from genetic interaction	19531352	MGI
acts upstream of or within muscle tissue morphogenesis	IGI IGI: Inferred from genetic interaction	19531352	MGI
acts upstream of or within muscle tissue morphogenesis	IMP IMP: Inferred from mutant phenotype	19531352	MGI
acts upstream of or within ossification	IMP IMP: Inferred from mutant phenotype	8587605	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	17855775	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	22638570	MGI
acts upstream of or within regulation of cell-matrix adhesion	IMP IMP: Inferred from mutant phenotype	16554364	MGI
acts upstream of or within skeletal muscle cell differentiation	IMP IMP: Inferred from mutant phenotype	22147266	MGI
acts upstream of or within skeletal muscle tissue development	IGI IGI: Inferred from genetic interaction	8269513	MGI
acts upstream of or within skeletal muscle tissue development	IMP IMP: Inferred from mutant phenotype	19531352	MGI
acts upstream of or within somitogenesis	IMP IMP: Inferred from mutant phenotype	8565825	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

myogenic factor 5

myogenic regulatory factor MYF-5

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08892	MYF5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22246	Myf5 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Myf5	NCBI	NCBI:4617

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