2. Gene
  3. Mef2d - myocyte enhancer factor 2D Gene

Mef2d - myocyte enhancer factor 2D Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 17261 | Gene type: protein coding

About Mef2d

Summary

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein dimerization activity. Acts upstream of or within several processes, including osteoblast differentiation; skeletal muscle cell differentiation; and skeletal system development. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; dorsal aorta; early conceptus; embryo mesenchyme; and genitourinary system. Orthologous to human MEF2D (myocyte enhancer factor 2D). [provided by Alliance of Genome Resources, Apr 2022]

Mef2d Products(32)

mRNA Protein Name
NM_001310587.2 NP_001297516.1 myocyte-specific enhancer factor 2D isoform 1
NM_001310593.2 NP_001297522.1 myocyte-specific enhancer factor 2D isoform 3
NM_001410077.1 NP_001397006.1 myocyte-specific enhancer factor 2D isoform 1
NM_001410078.1 NP_001397007.1 myocyte-specific enhancer factor 2D isoform 1
NM_001410079.1 NP_001397008.1 myocyte-specific enhancer factor 2D isoform 4
NM_001410080.1 NP_001397009.1 myocyte-specific enhancer factor 2D isoform 4
NM_001410081.1 NP_001397010.1 myocyte-specific enhancer factor 2D isoform 4
NM_001410082.1 NP_001397011.1 myocyte-specific enhancer factor 2D isoform 4
NM_001410083.1 NP_001397012.1 myocyte-specific enhancer factor 2D isoform 4
NM_001410084.1 NP_001397013.1 myocyte-specific enhancer factor 2D isoform 5
NM_001410085.1 NP_001397014.1 myocyte-specific enhancer factor 2D isoform 2
NM_001410086.1 NP_001397015.1 myocyte-specific enhancer factor 2D isoform 3
NM_001410087.1 NP_001397016.1 myocyte-specific enhancer factor 2D isoform 3
NM_001410088.1 NP_001397017.1 myocyte-specific enhancer factor 2D isoform 6
NM_001410089.1 NP_001397018.1 myocyte-specific enhancer factor 2D isoform 7
NM_001410090.1 NP_001397019.1 myocyte-specific enhancer factor 2D isoform 8
NM_001410091.1 NP_001397020.1 myocyte-specific enhancer factor 2D isoform 9
NM_001410092.1 NP_001397021.1 myocyte-specific enhancer factor 2D isoform 9
NM_001410093.1 NP_001397022.1 myocyte-specific enhancer factor 2D isoform 10
NM_001410094.1 NP_001397023.1 myocyte-specific enhancer factor 2D isoform 11
NM_001410095.1 NP_001397024.1 myocyte-specific enhancer factor 2D isoform 12
NM_001410096.1 NP_001397025.1 myocyte-specific enhancer factor 2D isoform 12
NM_001410097.1 NP_001397026.1 myocyte-specific enhancer factor 2D isoform 12
NM_001410098.1 NP_001397027.1 myocyte-specific enhancer factor 2D isoform 13
NM_001410099.1 NP_001397028.1 myocyte-specific enhancer factor 2D isoform 13
NM_001410100.1 NP_001397029.1 myocyte-specific enhancer factor 2D isoform 13
NM_001410101.1 NP_001397030.1 myocyte-specific enhancer factor 2D isoform 14
NM_001410102.1 NP_001397031.1 myocyte-specific enhancer factor 2D isoform 14
NM_001410103.1 NP_001397032.1 myocyte-specific enhancer factor 2D isoform 15
NM_001410104.1 NP_001397033.1 myocyte-specific enhancer factor 2D isoform 15
NM_001410105.1 NP_001397034.1 myocyte-specific enhancer factor 2D isoform 16
NM_133665.5 NP_598426.1 myocyte-specific enhancer factor 2D isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
15491989 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
7760790 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12130539 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
7760790 MGI
enables enzyme binding IPI
IPI: Inferred from physical interaction
20833138 MGI
enables histone deacetylase binding IDA
IDA: Inferred from direct assay
17158926 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
25331958 MGI
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
9858528 MGI
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
9858528 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
17336904 MGI
acts upstream of or within endochondral ossification IGI
IGI: Inferred from genetic interaction
17336904 MGI
acts upstream of or within osteoblast differentiation IGI
IGI: Inferred from genetic interaction
17336904 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
9738004 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17158926 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7760790 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
8900141 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12130539 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
22147266 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17158926 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15024082 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myocyte-specific enhancer factor 2D

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-128341 ERK5-IN-2 Inhibitor 98.96% Unkown
HY-139254 Indirubin-3′-oxime 99.10% Unkown
HY-RS08312 MEF2D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17303 Mef2d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23758 Mef2d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mef2d NCBI NCBI:4209