Bub1b - BUB1 mitotic checkpoint serine/threonine kinase B Gene

Rattus norvegicus

Gene ID: 171576 | Gene type: protein coding

About Bub1b

Summary

Predicted to enable protein kinase activity. Predicted to be involved in meiotic sister chromatid cohesion, centromeric and mitotic spindle assembly checkpoint signaling. Predicted to act upstream of or within metaphase/anaphase transition of mitotic cell cycle and protein localization to chromosome, centromeric region. Predicted to be located in cytosol; perinuclear region of cytoplasm; and spindle. Predicted to be part of outer kinetochore. Predicted to colocalize with kinetochore. Human ortholog(s) of this gene implicated in colorectal Cancer and mosaic variegated aneuploidy syndrome 1. Orthologous to human BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B). [provided by Alliance of Genome Resources, Apr 2022]

Bub1b Products(1)

mRNA	Protein	Name
NM_138540.1	NP_612549.1	mitotic checkpoint serine/threonine-protein kinase BUB1 beta

Protein Preferred Names

Protein Names

mitotic checkpoint serine/threonine-protein kinase BUB1 beta

BUB1B, mitotic checkpoint serine/threonine kinase	budding uninhibited by benzimidazoles 1 beta
budding uninhibited by benzimidazoles 1 homolog beta

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-161865	Antitumor agent-180	Inducer	99.46%	Unkown
HY-172089	TG101209 analog 1	Inducer	98.27%	Unkown
HY-RS01682	BUB1B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19413	Bub1b Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25905	Bub1b Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Bub1b	NCBI	NCBI:701

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