Ppp4c - protein phosphatase 4, catalytic subunit Gene

Rattus norvegicus

Also known as Ppx

Gene ID: 171366 | Gene type: protein coding

About Ppp4c

Summary

Enables lamin binding activity and Phosphatase activity. Involved in cellular response to interleukin-1 and dephosphorylation. Located in nucleus. Orthologous to human PPP4C (protein Phosphatase 4 catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]

Ppp4c Products(1)

mRNA	Protein	Name
NM_134359.1	NP_599186.1	serine/threonine-protein phosphatase 4 catalytic subunit

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables lamin binding	IDA IDA: Inferred from direct assay	16830232	RGD
enables phosphatase activity	IDA IDA: Inferred from direct assay	16830232	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	10769191	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to interleukin-1	IEP IEP: Inferred from expression pattern	16830232	RGD
involved in dephosphorylation	IDA IDA: Inferred from direct assay	16830232	RGD
involved in negative regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	28526910	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	16830232	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

serine/threonine-protein phosphatase 4 catalytic subunit

PP4C	pp4
protein phosphatase 4 (formerly X), catalytic subunit

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11028	PPP4C Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22739	Ppp4c Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS29253	Ppp4c Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ppp4c	NCBI	NCBI:5531

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