1. Gene
  2. Dusp5 - dual specificity phosphatase 5 Gene

Dusp5 - dual specificity phosphatase 5 Gene

Rattus norvegicus

Also known as Cpg21

Gene ID: 171109 | Gene type: protein coding

About Dusp5

Summary

Enables MAP kinase tyrosine/serine/threonine Phosphatase activity. Involved in negative regulation of transcription, DNA-templated; negative regulation of vasoconstriction; and positive regulation of cerebral blood circulation. Predicted to be active in cytoplasm and nucleus. Orthologous to human DUSP5 (dual specificity Phosphatase 5). [provided by Alliance of Genome Resources, Apr 2022]

Dusp5 Products(1)

mRNA Protein Name
NM_133578.2 NP_598262.2 dual specificity protein phosphatase 5
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables MAP kinase tyrosine/serine/threonine phosphatase activity IDA
IDA: Inferred from direct assay
9699150 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
9699150 RGD
involved in negative regulation of vasoconstriction IMP
IMP: Inferred from mutant phenotype
25397684 RGD
involved in positive regulation of cerebral blood circulation IMP
IMP: Inferred from mutant phenotype
25397684 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual specificity protein phosphatase 5

MAP-kinase phosphatase (cpg21)

MAP-kinase phosphatase CPG21

candidate plasticity-related gene 21

Orthologs Information

Species Symbol Source ID
Homo sapiens Dusp5 NCBI NCBI:1847