Dnph1 - 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Gene

Rattus norvegicus

Also known as Rcl; C6orf108; RGD620382

Gene ID: 171047 | Gene type: protein coding

About Dnph1

Summary

Enables deoxyribonucleoside 5'-monophosphate N-glycosidase activity and protein homodimerization activity. Involved in allantoin metabolic process; dGMP catabolic process; and positive regulation of cell growth. Located in nucleus. Orthologous to human DNPH1 (2'-deoxynucleoside 5'-phosphate N-hydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Dnph1 Products(1)

mRNA	Protein	Name
NM_133525.2	NP_598209.1	2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables deoxyribonucleoside 5'-monophosphate N-glycosidase activity	IDA IDA: Inferred from direct assay	17234634	RGD
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	17234634	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in allantoin metabolic process	IDA IDA: Inferred from direct assay	17234634	RGD
involved in dGMP catabolic process	IDA IDA: Inferred from direct assay	17234634	RGD
involved in deoxyribonucleoside monophosphate catabolic process	IDA IDA: Inferred from direct assay	17234634	RGD
involved in positive regulation of cell growth	IDA IDA: Inferred from direct assay	17234634	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	9271375	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

Nucleoside 2-deoxyribosyltransferase domain containing protein RGD620382	c-Myc-responsive protein Rcl
deoxyribonucleoside 5'-monophosphate N-glycosidase	putative c-Myc-responsive

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03915	DNPH1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19676	Dnph1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26169	Dnph1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dnph1	NCBI	NCBI:10591

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