2. Gene
  3. Ltk - leukocyte tyrosine kinase Gene

Ltk - leukocyte tyrosine kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 17005 | Gene type: protein coding

About Ltk

Summary

The protein encoded by this gene is a member of the ros/Insulin Receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Four alternatively spliced transcript variants encoding different isoforms have been described for this gene. These transcripts are expressed in a tissue-specific manner in lymphocytes, brain and neuroblastoma cells, and the encoded isoforms exhibit different subcellular localization. The lymphocyte and brain specific variants initiate translation at non-AUG (CUG) start codons. [provided by RefSeq, Jul 2008]

Ltk Products(4)

mRNA Protein Name
NM_008523.2 NP_032549.2 leukocyte tyrosine kinase receptor isoform A
NM_203345.2 NP_976220.2 leukocyte tyrosine kinase receptor isoform D precursor
NM_206941.1 NP_996824.1 leukocyte tyrosine kinase receptor isoform B
NM_206942.2 NP_996825.2 leukocyte tyrosine kinase receptor isoform C precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in membrane IDA
IDA: Inferred from direct assay
2836739 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leukocyte tyrosine kinase receptor

leukocyte receptor tyrosine kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-155516 KV1.3-IN-1 Inhibitor 98.34% Unkown
HY-131909 CJ-2360 Inhibitor / Unkown
HY-108263B (R)-3-Hydroxy Midostaurin Inhibitor / Unkown
HY-110347 Mps1-IN-1 dihydrochloride Inhibitor / Unkown
HY-12962A NMDA-IN-1 dihydrochloride Antagonist / Unkown
HY-145256 GABAA receptor agent 4 Antagonist / Unkown
HY-145257 GABAA receptor agent 5 Antagonist / Unkown
HY-15018A SSR126768A free base Antagonist / Unkown
HY-176305S Neurofilament, U-15N / Unkown
HY-RS07884 LTK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19111 Ltk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25601 Ltk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ltk NCBI NCBI:4058