2. Gene
  3. Mycl - v-myc avian myelocytomatosis viral oncogene lung carcinoma derived Gene

Mycl - v-myc avian myelocytomatosis viral oncogene lung carcinoma derived Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as L-myc; Lmyc1; Mycl1; Lmyc-1; bHLHe38

Gene ID: 16918 | Gene type: protein coding

About Mycl

Summary

This gene encodes a basic helix-loop-helix leucine zipper (bHLHZip) protein that heterodimerizes with another bHLHZip protein to drive transcription of targets important for proliferation, Apoptosis and differentiation. Mice lacking this gene product show marked decrease in T-cell priming during Bacterial and viral infections. In humans, this gene was found to be amplified in small-cell lung cancers. Alternate splicing of this gene results in multiple variants. [provided by RefSeq, Dec 2014]

Mycl Products(2)

mRNA Protein Name
NM_001303121.1 NP_001290050.1 protein L-Myc isoform 2
NM_008506.3 NP_032532.1 protein L-Myc isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
10229200 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within regulation of inner ear auditory receptor cell differentiation IGI
IGI: Inferred from genetic interaction
23022312 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein L-Myc

L-myc-1 proto-oncogene protein

lung carcinoma myc related oncogene 1

protein L-Myc-1

v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived

v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08883 MYCL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20778 Mycl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27292 Mycl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mycl NCBI NCBI:4610