2. Gene
  3. Kif7 - kinesin family member 7 Gene

Kif7 - kinesin family member 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 16576 | Gene type: protein coding

About Kif7

Summary

Enables identical protein binding activity. Involved in negative regulation of smoothened signaling pathway and positive regulation of smoothened signaling pathway. Acts upstream of or within aorta development; cardiac septum development; and coronary vasculature development. Located in ciliary basal body. Is expressed in metanephros and testis. Used to study acrocallosal syndrome; ciliopathy; congenital diaphragmatic hernia; and hydrolethalus syndrome. Human ortholog(s) of this gene implicated in acrocallosal syndrome; cleft lip; and hydrolethalus syndrome 2. Orthologous to human KIF7 (Kinesin family member 7). [provided by Alliance of Genome Resources, Apr 2022]

Kif7 Products(4)

mRNA Protein Name
NM_001291222.2 NP_001278151.1 kinesin-like protein KIF7 isoform 1
NM_001412613.1 NP_001399542.1 kinesin-like protein KIF7 isoform 3
NM_001412614.1 NP_001399543.1 kinesin-like protein KIF7 isoform 4
NM_010626.3 NP_034756.2 kinesin-like protein KIF7 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
24952464 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19549984 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within aorta development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within cardiac septum development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within coronary vasculature development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
involved in negative regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
19549984 MGI
involved in positive regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
19549984 MGI
Cellular Component GO Annotation Evidence Reference Source
located in ciliary basal body IDA
IDA: Inferred from direct assay
25644602 MGI
located in ciliary tip IDA
IDA: Inferred from direct assay
29038301 MGI
located in cilium IDA
IDA: Inferred from direct assay
19666503 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin-like protein KIF7

kinesin 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07295 KIF7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22213 Kif7 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif7 NCBI NCBI:374654