2. Gene
  3. Kif11 - kinesin family member 11 Gene

Kif11 - kinesin family member 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Eg5; Kif8; Kifl1; Knsl1

Gene ID: 16551 | Gene type: protein coding

About Kif11

Summary

Predicted to enable plus-end-directed microtubule motor activity and protein kinase binding activity. Acts upstream of or within mitotic centrosome separation and spindle assembly. Predicted to be located in cytosol; microtubule; and mitotic spindle. Predicted to be part of protein-containing complex. Predicted to be active in nucleus and spindle microtubule. Predicted to colocalize with spindle pole. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in microcephaly with or without chorioretinopathy, lymphedema, or mental retardation. Orthologous to human KIF11 (Kinesin family member 11). [provided by Alliance of Genome Resources, Apr 2022]

Kif11 Products(1)

mRNA Protein Name
NM_010615.2 NP_034745.1 kinesin-like protein KIF11
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within mitotic centrosome separation IMP
IMP: Inferred from mutant phenotype
12840069 MGI
acts upstream of or within spindle assembly IMP
IMP: Inferred from mutant phenotype
22851319 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin-like protein KIF11

kinesin-like 1

kinesin-related motor protein Eg5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07255 KIF11 Human Pre-designed siRNA Set A / Unkown
HY-RS18526 Kif11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25008 Kif11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif11 NCBI NCBI:3832