Jund - jun D proto-oncogene Gene

Mus musculus

Also known as Jund1

Gene ID: 16478 | Gene type: protein coding

About Jund

Summary

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and Apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013]

Jund Products(2)

mRNA	Protein	Name
NM_001286944.1	NP_001273873.1	transcription factor JunD isoform deltaJunD
NM_010592.5	NP_034722.1	transcription factor JunD isoform JunD-FL

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	12220541	MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	2504580	MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IMP IMP: Inferred from mutant phenotype	2504580	MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	10837920	MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IMP IMP: Inferred from mutant phenotype	2504580	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	22974638	MGI
enables transcription cis-regulatory region binding	IDA IDA: Inferred from direct assay	22990073	MGI
enables transcription coregulator binding	IPI IPI: Inferred from physical interaction	10523647	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular response to calcium ion	IDA IDA: Inferred from direct assay	19303854	MGI
acts upstream of or within gene expression	IMP IMP: Inferred from mutant phenotype	22990073	MGI
acts upstream of or within osteoblast development	IGI IGI: Inferred from genetic interaction	15563473	MGI
acts upstream of or within positive regulation of osteoblast differentiation	IGI IGI: Inferred from genetic interaction	15563473	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	2504580	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	19303854	MGI
involved in positive regulation of transcription by RNA polymerase II	IGI IGI: Inferred from genetic interaction	10523647	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

transcription factor JunD

Jun proto-oncogene related gene d	Jun proto-oncogene related gene d1
transcription factor AP-1 subunit JunD	transcription factor jun-D

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07060	JUND Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-171205	In vivo Jund Mouse Pre-designed siRNA-1	Pre-designed Sets	/	Unkown
HY-171206	In vivo Jund Mouse Pre-designed siRNA-2	Pre-designed Sets	/	Unkown
HY-171207	In vivo Jund Mouse Pre-designed siRNA-3	Pre-designed Sets	/	Unkown
HY-RS19345	Jund Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25836	Jund Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Jund	NCBI	NCBI:3727

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