2. Gene
  3. Itgb7 - integrin beta 7 Gene

Itgb7 - integrin beta 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ly69

Gene ID: 16421 | Gene type: protein coding

About Itgb7

Summary

Predicted to enable Integrin binding activity. Acts upstream of or within T cell migration. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of Integrin alpha4-beta7 complex. Predicted to be active in cell surface and focal adhesion. Is expressed in genitourinary system and thymus primordium. Orthologous to human ITGB7 (Integrin subunit beta 7). [provided by Alliance of Genome Resources, Apr 2022]

Itgb7 Products(1)

mRNA Protein Name
NM_013566.2 NP_038594.2 integrin beta-7 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within T cell migration IMP
IMP: Inferred from mutant phenotype
23661644 MGI
acts upstream of or within leukocyte migration IMP
IMP: Inferred from mutant phenotype
15484189 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin beta-7

M290 IEL antigen

integrin beta-P

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99184 Abrilumab 98.35% Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06971 ITGB7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18178 Itgb7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24652 Itgb7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itgb7 NCBI NCBI:3695
Macaca fascicularis Itgb7 NCBI NCBI:102137082