2. Gene
  3. Irs4 - insulin receptor substrate 4 Gene

Irs4 - insulin receptor substrate 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as IRS-4

Gene ID: 16370 | Gene type: protein coding

About Irs4

Summary

Predicted to enable Insulin Receptor binding activity and phosphatidylinositol 3-kinase binding activity. Predicted to be involved in Insulin Receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in cytosol and plasma membrane. Is expressed in several structures, including alimentary system; brain; branchial arch; eye; and genitourinary system. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 9. Orthologous to human IRS4 (Insulin Receptor substrate 4). [provided by Alliance of Genome Resources, Apr 2022]

Irs4 Products(1)

mRNA Protein Name
NM_010572.2 NP_034702.2 insulin receptor substrate 4
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12052866 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin receptor substrate 4

phosphoprotein of 160 kDa

pp160

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06919 IRS4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21358 Irs4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27877 Irs4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Irs4 NCBI NCBI:8471